Dr. Micheál Mac Aogáin

Dr. Micheál Mac Aogáin

Clinical Senior Lecturer, Clinical Medicine

www.michealmacaogain.com

Publications and Further Research Outputs

  • Michel Mac Aogin, Geraldine Moloney, Shauna Kilkenny, Mary Kelleher, May Kelleghan, Brieda Boyle, Thomas Rogers, Whole-genome sequencing improves discrimination of relapse from reinfection and identifies transmission events among patients with recurrent Clostridium difficile infections, Journal of Hospital Infection, 2015Journal Article, 2015
  • Yvonne Lynagh, Michel Mac Aogin, Thomas Rogers, Magnus Unemo, Brendan Crowley, Detailed characterisation of the first high-level azithromycin-resistant Neisseria gonorrhoeae cases in Ireland, The Journal of Antimicrobial Chemotherapy, 2015Journal Article, 2015
  • Roycroft E, Mac Aogin M, O'Toole RF, Fitzgibbon M, Rogers TR, Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis in Ireland., Genome announcements, 2, (5), 2014Journal Article, 2014, DOI , TARA - Full Text
  • Mac Aogin M, Bower JE, Basu I, Freeman JT, O'Toole RF, Draft Genome Sequence of a Drug-Susceptible New Zealand Isolate of Mycobacterium tuberculosis Lineage 3., Genome announcements, 3, (3), 2014Journal Article, 2014, DOI , TARA - Full Text
  • Brown AF, Murphy AG, Lalor SJ, Leech JM, O'Keeffe KM, Mac Aogin M, O'Halloran DP, Lacey KA, Tavakol M, Hearnden CH, Fitzgerald-Hughes D, Humphreys H, Fennell JP, van Wamel WJ, Foster TJ, Geoghegan JA, Lavelle EC, Rogers TR, McLoughlin RM, Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection., PLoS pathogens, 11, (11), 2015, pe1005226Journal Article, 2015, DOI , TARA - Full Text
  • Miajlovic H, Mac Aogin M, Collins CJ, Rogers TR, Smith SG, Characterization of Escherichia coli bloodstream isolates associated with mortality., Journal of medical microbiology, 2015Journal Article, 2015
  • Kinnevey PM, Shore AC, Mac Aogin M, Creamer E, Brennan GI, Humphreys H, Rogers TR, O'Connell B, Coleman DC, Enhanced tracking of the nosocomial transmission of endemic ST22-MRSA-IV among patients and environmental sites using whole-genome sequencing., Journal of clinical microbiology, 2015Journal Article, 2015
  • Michel Mac Aogin. Shauna Kilkenny, Claire Walsh, Sinad Lindsay, Geraldine Moloney, Trefor Morris, Sophie Jones, Thomas R. Rogers, Identification of a novel mutation at the primary dimer interface of GyrA conferring fluoroquinolone resistance in Clostridium difficile, Journal of Global Antimicrobial Resistance, 2015Journal Article, 2015, URL , TARA - Full Text
  • Moloney G, Mac Aogin M, Kelleghan M, O'Connell B, Hurley C, Montague E, Conlon M, Murray H, Rogers TR, Possible Interplay Between Hospital and Community Transmission of a Novel Clostridium Difficile Sequence Type 295 Recognized by Next-Generation Sequencing., Infection control and hospital epidemiology, 37, (6), 2016, p680-4Journal Article, 2016, DOI
  • Miche􏰀al Mac Aog􏰀ain, Helen Miajlovic, Geraldine Moloney, Sanjay H. Chotirmall, Thomas R. Rogers and Stephen G. J. Smith, Identification of a novel sequence type of Escherichia coli as the causative agent of pyelonephritis and bloodstream infection, JMM Case Reports, 3, 2016, p1 - 4Journal Article, 2016, DOI , URL , TARA - Full Text
  • McElroy MC, Hill M, Moloney G, Mac Aogin M, McGettrick S, O'Doherty , Rogers TR., Typhlocolitis associated with Clostridium difficile ribotypes 078 and 110 in neonatal piglets from a commercial Irish pig herd., Irish Veterinary Journal, 69, (10), 2016Journal Article, 2016, URL
  • Kinnevey PM, Shore AC, Mac Aogin M, Creamer E, Brennan GI, Humphreys H, Rogers TR, O'Connell B, Coleman DC., Enhanced Tracking of Nosocomial Transmission of Endemic Sequence Type 22 Methicillin-Resistant Staphylococcus aureus Type IV Isolates among Patients and Environmental Sites by Use of Whole-Genome Sequencing., Journal of Clinical Microbiology, 54, (2), 2016, p445 - 448Journal Article, 2016, URL
  • Lynch M, Walsh TA, Marszalowska I, Webb AE, MacAogain M, Rogers TR, Windle H, Kelleher D, O'Connell MJ, Loscher CE., Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response., BMC Evolutionary Biology, 17, (1), 2017, p90 - 90Journal Article, 2017, URL
  • Mac Aogin M, Miajlovic H, Moloney G, Chotirmall SH, Rogers TR, Smith SG., Identification of a novel sequence type of Escherichia coli as the causative agent of pyelonephritis and bloodstream infection., JMM Case Reports, 3, (5), 2016Journal Article, 2016, URL
  • Lynch M, Walsh TA, Marszalowska I, Webb AE, Mac Aogin M, Rogers TR, Windle H, Kelleher D, O'Connell MJ, Loscher CE, Erratum to: Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response., BMC Evolutionary Biology, 17, (1), 2017, p135-Journal Article, 2017, URL
  • Mac Aogin M, Fennelly N, Walsh A, Lynagh Y, Bekaert M, Lawlor B, Walsh P , Kelly B, Rogers TR, Crowley B , Fourteen Draft Genome Sequences for the First Reported Cases of Azithromycin-Resistant Neisseria gonorrhoeae in Ireland., Genome Announcements, 5, (23), 2017Journal Article, 2017
  • Gautam, S.S. and Aogin, M.M. and O'Toole, R.F., Draft genome sequence of the first confirmed isolate of multidrug-resistant Mycobacterium tuberculosis in Tasmania, Genome Announcements, 5, (44), 2017, pe01230-17Journal Article, 2017, DOI , URL , TARA - Full Text
  • Aogin, M.M. and Gautam, S.S. and Bower, J.E. and Basu, I. and O'Toole, R.F., Draft genome sequence of a New Zealand Rangipo strain of Mycobacterium tuberculosis, Genome Announcements, 4, (4), 2016, pe00657-16Journal Article, 2016, DOI , URL , TARA - Full Text
  • Gautam, S.S. and Aogin, M.M. and Cooley, L.A. and Haug, G. and Fyfe, J.A. and Globan, M. and O Toole, R.F., Molecular epidemiology of tuberculosis in Tasmania and genomic characterisation of its first known multi-drug resistant case, PLoS ONE, 13, (2), 2018, p1--Journal Article, 2018, DOI , URL , TARA - Full Text
  • Gautam S.S, Haug G, Cooley L.A, Mac Aogin M, O'Toole R.F, Intercontinental translocation of latent multidrug-resistant tuberculosis to Australia demonstrated by whole genome sequencing, Medical Journal of Australia, 210, (5), 2019, p236 - 236.e1Journal Article, 2019, DOI , URL
  • Tiew PY, Mac Aogain M, Ali NABM, Thng KX, Goh K, Lau KJX, Chotirmall SH., The Mycobiome in Health and Disease: Emerging Concepts, Methodologies and Challenges., Mycopathologia, 185, (2), 2020, p207-231Journal Article, 2020, DOI
  • Al Alam D, Danopoulos S, Grubbs B, Ali NABM, MacAogain M, Chotirmall SH, Warburton D, Gaggar A, Ambalavanan N, Lal CV., Human Fetal Lungs Harbor a Microbiome Signature., American journal of respiratory and critical care medicine, 201, (8), 2020, p1002-1006Journal Article, 2020, DOI
  • Al Alam D, Danopoulos S, Grubbs B, Ali NABM, Mac Aogin M, Chotirmall SH, Warburton D, Gaggar A, Ambalavanan N, Lal CV., Reply to de Steenhuijsen Piters and Bogaert: Bacterial DNA in Fetal Lung Samples May Be Explained by Sample Contamination., American journal of respiratory and critical care medicine, 201, (10), 2020, p1311-1312Journal Article, 2020, DOI
  • Tiew PY, Ko FWS, Narayana JK, Poh ME, Xu H, Neo HY, Loh LC, Ong CK, Mac Aogin M, Tan JHY, Kamaruddin NH, Sim GJH, Lapperre TS, Koh MS, Hui DSC, Abisheganaden JA, Tee A, Tsaneva-Atanasova K, Chotirmall SH., "High-Risk" Clinical and Inflammatory Clusters in COPD of Chinese Descent., Chest, 158, (1), 2020, p145-156Journal Article, 2020, DOI
  • Palanivel M, Mac Aogin M, Purbojati RW, Uchida A, Aung NW, Lim SBY, Putra A, Drautz-Moses DI, Seaton S, Rogers TR, Schuster SC, Chotirmall SH., Whole-Genome Sequencing of Aspergillus terreus Species Complex., Mycopathologia, 185, (2), 2020, p405-408Journal Article, 2020, DOI
  • Poh TY, Tiew PY, Lim AYH, Thng KX, Binte Mohamed Ali NA, Narayana JK, Mac Aogin M, Tien Z, Chew WM, Wai Chan AK, Keir HR, Dicker AJ, Hassan TM, Xu H, Tee AKH, Ong TH, Koh MS, Abisheganaden JA, Chalmers JD, Chotirmall SH., Increased Chitotriosidase Is Associated With Aspergillus and Frequent Exacerbations in South-East Asian Patients With Bronchiectasis., Chest, 158, (2), 2020, p512-522Journal Article, 2020, DOI
  • Mac Aogin M, Lau KJX, Cai Z, Kumar Narayana J, Purbojati RW, Drautz-Moses DI, Gaultier NE, Jaggi TK, Tiew PY, Ong TH, Siyue Koh M, Lim Yick Hou A, Abisheganaden JA, Tsaneva-Atanasova K, Schuster SC, Chotirmall SH., Metagenomics Reveals a Core Macrolide Resistome Related to Microbiota in Chronic Respiratory Disease., American journal of respiratory and critical care medicine, 202, (3), 2020, p433-447Journal Article, 2020, DOI
  • Tiew PY, Ko FWS, Pang SL, Matta SA, Sio YY, Poh ME, Lau KJX, Mac Aogin M, Jaggi TK, Ivan FX, Gaultier NE, Uchida A, Drautz-Moses DI, Xu H, Koh MS, Hui DSC, Tee A, Abisheganaden JA, Schuster SC, Chew FT, Chotirmall SH., Environmental fungal sensitisation associates with poorer clinical outcomes in COPD., The European respiratory journal, 56, (2), 2020Journal Article, 2020, DOI
  • Binte Mohamed Ali NA, Ivan FX, Aogin MM, Narayana JK, Lee SY, Lim CL, Chotirmall SH., THE HEALTHY AIRWAY MYCOBIOME IN INDIVIDUALS OF ASIAN DESCENT., Chest, 2020Journal Article, 2020, DOI
  • Tiew PY, Dicker AJ, Keir HR, Poh ME, Pang SL, Mac Aogin M, Chua Qi Yu B, Tan JL, Xu H, Koh MS, Tee A, Abisheganaden JA, Chew FT, Miller BE, Tal-Singer R, Chalmers JD, Chotirmall SH., A high-risk airway mycobiome is associated with frequent exacerbation and mortality in COPD., The European respiratory journal, 2020Journal Article, 2020, DOI
  • Mac Aogin M, Tiew PY, Lim AYH, Low TB, Tan GL, Hassan T, Ong TH, Pang SL, Lee ZY, Gwee XW, Martinus C, Sio YY, Matta SA, Ong TC, Tiong YS, Wong KN, Narayanan S, Au VB, Marlier D, Keir HR, Tee A, Abisheganaden JA, Koh MS, Wang Y, Connolly JE, Chew FT, Chalmers JD, Chotirmall SH., Distinct "Immunoallertypes" of Disease and High Frequencies of Sensitization in Non-Cystic Fibrosis Bronchiectasis., American journal of respiratory and critical care medicine, 199, (7), 2019, p842-853Journal Article, 2019, DOI
  • Mac Aogin M, Chotirmall SH., Bronchiectasis and cough: An old relationship in need of renewed attention., Pulmonary pharmacology & therapeutics, 57, 2019, p101812Journal Article, 2019, DOI
  • Mac Aogin M, Chaturvedi V, Chotirmall SH., MycopathologiaGENOMES: The New 'Home' for the Publication of Fungal Genomes., Mycopathologia, 184, (5), 2019, p551-554Journal Article, 2019, DOI
  • Gautam SS, Kc R, Leong KW, Mac Aogin M, O'Toole RF., A step-by-step beginner's protocol for whole genome sequencing of human bacterial pathogens., Journal of biological methods, 6, (1), 2019, pe110Journal Article, 2019, DOI
  • Ali NABM, Mac Aogin M, Morales RF, Tiew PY, Chotirmall SH., Optimisation and Benchmarking of Targeted Amplicon Sequencing for Mycobiome Analysis of Respiratory Specimens., International journal of molecular sciences, 20, (20), 2019Journal Article, 2019, DOI
  • Lee SY, Mac Aogin M, Fam KD, Chia KL, Binte Mohamed Ali NA, Yap MMC, Yap EPH, Chotirmall SH, Lim CL., Airway microbiome composition correlates with lung function and arterial stiffness in an age-dependent manner., PloS one, 14, (11), 2019, pe0225636Journal Article, 2019, DOI
  • Yong VFL, Soh MM, Jaggi TK, Mac Aogin M, Chotirmall SH., The Microbial Endocrinology of Pseudomonas aeruginosa: Inflammatory and Immune Perspectives., Archivum immunologiae et therapiae experimentalis, 66, (5), 2018, p329-339Journal Article, 2018, DOI
  • Lawlor B, Lynch R, Mac Aogin M, Walsh P., Field of genes: using Apache Kafka as a bioinformatic data repository., GigaScience, 7, (4), 2018Journal Article, 2018, DOI
  • Chandrasekaran R, Mac Aogin M, Chalmers JD, Elborn SJ, Chotirmall SH., Geographic variation in the aetiology, epidemiology and microbiology of bronchiectasis., BMC pulmonary medicine, 18, (1), 2018, p83Journal Article, 2018, DOI
  • Mac Aogin M, Chandrasekaran R, Lim AYH, Low TB, Tan GL, Hassan T, Ong TH, Hui Qi Ng A, Bertrand D, Koh JY, Pang SL, Lee ZY, Gwee XW, Martinus C, Sio YY, Matta SA, Chew FT, Keir HR, Connolly JE, Abisheganaden JA, Koh MS, Nagarajan N, Chalmers JD, Chotirmall SH., Immunological corollary of the pulmonary mycobiome in bronchiectasis: the CAMEB study., The European respiratory journal, 52, (1), 2018Journal Article, 2018, DOI
  • Ryan L, Golparian D, Fennelly N, Rose L, Walsh P, Lawlor B, Mac Aogin M, Unemo M, Crowley B., Antimicrobial resistance and molecular epidemiology using whole-genome sequencing of Neisseria gonorrhoeae in Ireland, 2014-2016: focus on extended-spectrum cephalosporins and azithromycin., European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 37, (9), 2018, p1661-1672Journal Article, 2018, DOI
  • Poh TY, Ali NABM, Mac Aogin M, Kathawala MH, Setyawati MI, Ng KW, Chotirmall SH., Inhaled nanomaterials and the respiratory microbiome: clinical, immunological and toxicological perspectives., Particle and fibre toxicology, 15, (1), 2018, p46Journal Article, 2018, DOI
  • Chotirmall SH, Gellatly SL, Budden KF, Mac Aogain M, Shukla SD, Wood DL, Hugenholtz P, Pethe K, Hansbro PM., Microbiomes in respiratory health and disease: An Asia-Pacific perspective., Respirology (Carlton, Vic.), 22, (2), 2017, p240-250Journal Article, 2017, DOI
  • Poh TY, Mac Aogin M, Chan AK, Yii AC, Yong VF, Tiew PY, Koh MS, Chotirmall SH., Understanding COPD-overlap syndromes., Expert review of respiratory medicine, 11, (4), 2017, p285-298Journal Article, 2017, DOI
  • Leung JM, Tiew PY, Mac Aogin M, Budden KF, Yong VF, Thomas SS, Pethe K, Hansbro PM, Chotirmall SH., The role of acute and chronic respiratory colonization and infections in the pathogenesis of COPD., Respirology (Carlton, Vic.), 22, (4), 2017, p634-650Journal Article, 2017, DOI
  • Gautam SS, Mac Aogin M, Bower JE, Basu I, O'Toole RF., Differential carriage of virulence-associated loci in the New Zealand Rangipo outbreak strain of Mycobacterium tuberculosis., Infectious diseases (London, England), 49, (9), 2017, p680-688Journal Article, 2017, DOI
  • Michel Mac Aogin, Jayanth Kumar Narayana, Pei Yee Tiew, Nur A"tikah Binte Mohamed Ali, Valerie Fei Lee Yong, Tavleen Kaur Jaggi, Albert Yick Hou Lim, Holly R. Keir, Alison J. Dicker, Kai Xian Thng, Akina Tsang, Fransiskus Xaverius Ivan, Mau Ern Poh, Martina Oriano, Stefano Aliberti, Francesco Blasi, Teck Boon Low, Thun How Ong, Brian Oliver, Yan Hui Giam, Augustine Tee, Mariko Siyue Koh, John Arputhan Abisheganaden, Krasimira Tsaneva-Atanasova, James D. Chalmers, Sanjay H. Chotirmall, Integrative microbiomics in bronchiectasis exacerbations, Nature Medicine, 2021Journal Article, 2021, DOI
  • Tiew, P.Y., Ko, F.W.S., Narayana, J.K., Poh, M.E., Xu, H., Neo, H.Y., Loh, L.-C., Ong, C.K., Mac Aogin, M., Tan, J.H.Y., Kamaruddin, N.H., Sim, G.J.H., Lapperre, T.S., Koh, M.S., Hui, D.S.C., Abisheganaden, J.A., Tee, A., Tsaneva-Atanasova, K., Chotirmall, S.H., "High-Risk" Clinical and Inflammatory Clusters in COPD of Chinese Descent, Chest, 158, (1), 2020, p145-156Journal Article, 2020, DOI
  • Jayanth Kumar Narayana, Michel Mac Aogin, Nur A'tikah Binte Mohamed Ali, Krasimira Tsaneva-Atanasova, Sanjay H. Chotirmall, Similarity network fusion for the integration of multi-omics and microbiomes in respiratory disease, European Respiratory Journal, 58, (2), 2021, p2101016Journal Article, 2021, DOI
  • Mac Aogin M, Mooij MJ, McCarthy RR, Plower E, Wang YP, Tian ZX, Dobson A, Morrissey J, Adams C, O'Gara F, The non-classical ArsR-family repressor PyeR (PA4354) modulates biofilm formation in Pseudomonas aeruginosa., Microbiology (Reading, England), 158, (Pt 10), 2012, p2598-609Journal Article, 2012
  • Mac Aogin M, Kulah C, Rijnsburger M, Celebi G, Savelkoul PH, O'Gara F, Mooij MJ, Characterization of imipenem resistance mechanisms in Pseudomonas aeruginosa isolates from Turkey., Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 18, (7), 2012, pE262-5Journal Article, 2012
  • Fargier E, Mac Aogin M, Mooij MJ, Woods DF, Morrissey JP, Dobson AD, Adams C, O'Gara F, MexT functions as a redox-responsive regulator modulating disulfide stress resistance in Pseudomonas aeruginosa., Journal of bacteriology, 194, (13), 2012, p3502-11Journal Article, 2012
  • Mac Aogin M, Mooij MJ, Adams C, Clair J, O'Gara F, Emergence of extended-spectrum beta-lactamase and fluoroquinolone resistance genes among Irish multidrug-resistant isolates., Diagnostic microbiology and infectious disease, 67, (1), 2010, p106-9Journal Article, 2010
  • Tian ZX, Fargier E, Mac Aogin M, Adams C, Wang YP, O'Gara F, Transcriptome profiling defines a novel regulon modulated by the LysR-type transcriptional regulator MexT in Pseudomonas aeruginosa., Nucleic acids research, 37, (22), 2009, p7546-59Journal Article, 2009
  • Tian ZX, Mac Aogin M, O'Connor HF, Fargier E, Mooij MJ, Adams C, Wang YP, O'Gara F, MexT modulates virulence determinants in Pseudomonas aeruginosa independent of the MexEF-OprN efflux pump., Microbial pathogenesis, 47, (4), 2009, p237-41Journal Article, 2009
  • O'Toole RF, Johari BM, Mac Aogin M, Rogers TR, Bower JE, Basu I, Freeman JT., Short communication, Genome Announcements, 2 , (3), 2014, pe00319-14Journal Article, 2014, DOI , URL
  • Roycroft E, Mac Aogin M, O'Toole RF, Fitzgibbon M, Rogers TR., Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis in Ireland., Genome announcements, 2014, ppii: e01002-14Journal Article, 2014
  • Mac Aogin M, Johari BM, Bower JE, O'Toole RF, Draft Genome Sequence of a Multidrug-Resistant New Zealand Isolate of Mycobacterium tuberculosis Lineage 3., Genome announcements, 2, (5), 2014Journal Article, 2014, DOI , URL , TARA - Full Text
  • Mac Aogin M, Roycroft E, Raftery P, Mok S, Fitzgibbon M, Rogers TR., Draft Genome Sequences of Three Mycobacterium chimaera Respiratory Isolates., Genome Announcements, 3, (6), 2015Journal Article, URL
  • Mac Aogin M, Rogers TR, Crowley B., Identification of emergent bla CMY-2 -carrying Proteus mirabilis lineages by whole-genome sequencing., New Microbes and New Infections, 27, (9), 2015, p58 - 62Journal Article, URL